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Thesis

Transcriptional brain networks and their key regulators across the human lifespan

Abstract:

The human brain’s transcriptome undergoes substantial changes over the lifespan and shows characteristic patterns that reflect anatomical regions and cellular compositions. In this thesis, I applied combinations of network algorithms and tools from computational biology to analyse transcriptional networks and their key regulators in the human brain across space (brain regions) and time (the human life course). First, I identified an age-dependent transcriptional network enriched for microg...

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Institution:
University of Oxford
Oxford college:
Magdalen College
Department:
Medical Sciences Division - Physiology,Anatomy and Genetics,Department of
Role:
Author

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Role:
Supervisor
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Funding agency for:
Claudia Constanze Wehrspaun
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:8f6e0ce4-86ea-4034-ad16-753edb7717de
Local pid:
ora:9562

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