Journal article
The causal roles of vitamin B12 and transcobalamin in prostate cancer: can Mendelian randomization analysis provide definitive answers?
- Abstract:
-
Circulating vitamin B12 (cobalamin/B12) and total transcobalamin (tTC) have been associated with increased and reduced risk, respectively, of prostate cancer. Mendelian randomization has the potential to determine whether these are causal associations. We estimated associations of single nucleotide polymorphisms in B12-related genes (MTR, MTRR, FUT2, TCN2, TCN1, CUBN, and MUT) with plasma concentrations of B12, tTC, holo-transcobalamin, holo-haptocorrin, folate, and homocysteine and with pros...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
G0601625/Medical Research Council
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G0900871/Medical Research Council
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NF-SI-0509-10242/Department of Health
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G0600705/Medical Research Council
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Bibliographic Details
- Publisher:
- e-Century Publishing Publisher's website
- Journal:
- International Journal of Molecular Epidemiology and Genetics, IJMEG Journal website
- Volume:
- 02
- Issue:
- 04
- Pages:
- 316-327
- Publication date:
- 2011-12-15
- Acceptance date:
- 2011-08-23
- EISSN:
-
1948-1756
- Pmid:
-
22199995
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:222339
- UUID:
-
uuid:8f4a689b-0c86-4229-ac2e-00e28dfab693
- Local pid:
- pubs:222339
- Source identifiers:
-
222339
- Deposit date:
- 2016-12-18
Terms of use
- Copyright holder:
- International Journal of Molecular Epidemiology and Genetics, IJMEG
- Copyright date:
- 2011
- Notes:
- IJMEG Copyright © 2011. The final version is available online from International Journal of Molecular Epidemiology and Genetics, IJMEG at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243448/
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