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Journal article

The importance of hypoxia in radiotherapy for the immune response, metastatic potential and FLASH-RT

Abstract:
Purpose: Hypoxia (low oxygen) is a common feature of solid tumours that has been intensely studied for more than six decades. Here we review the importance of hypoxia to radiotherapy with a particular focus on the contribution of hypoxia to immune responses, metastatic potential and FLASH radiotherapy, active areas of research by leading women in the field.
Conclusion: Although hypoxia-driven metastasis and immunosuppression can negatively impact clinic... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1080/09553002.2021.1988178

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Research group:
CRUK/MRC Ox Inst for Radiation Oncology
Role:
Author
Publisher:
Taylor and Francis Publisher's website
Journal:
International Journal of Radiation Biology Journal website
Volume:
98
Issue:
3
Pages:
439-451
Publication date:
2021-11-02
Acceptance date:
2021-09-28
DOI:
EISSN:
1362-3095
ISSN:
0955-3002
Language:
English
Keywords:
Pubs id:
1205972
Local pid:
pubs:1205972
Deposit date:
2021-10-28

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