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Journal article

Effect of Delta variant on viral burden and vaccine effectiveness against new SARS-CoV-2 infections in the UK

Abstract:

The effectiveness of the BNT162b2 and ChAdOx1 vaccines against new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections requires continuous re-evaluation, given the increasingly dominant B.1.617.2 (Delta) variant. In this study, we investigated the effectiveness of these vaccines in a large, community-based survey of randomly selected households across the United Kingdom. We found that the effectiveness of BNT162b2 and ChAdOx1 against infections (new polymerase chain reacti...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41591-021-01548-7

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Role:
Author
ORCID:
0000-0001-7097-8950
More by this author
Institution:
University of Oxford
Division:
MSD
Sub department:
BR MEDICAL SCIENCES DIV OFFICE; HB NDM EXPERIMENTAL MEDICINE
Oxford college:
Harris Manchester College
Role:
Author
ORCID:
0000-0002-4036-4269
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
ORCID:
0000-0002-4508-7969
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Wellcome Trust More from this funder
Publisher:
Springer Nature Publisher's website
Journal:
Nature Medicine Journal website
Volume:
27
Issue:
12
Pages:
2127-2135
Place of publication:
United States
Publication date:
2021-10-14
Acceptance date:
2021-09-21
DOI:
EISSN:
1546-170X
ISSN:
1078-8956
Pmid:
34650248
Language:
English
Keywords:
Pubs id:
1204210
Local pid:
pubs:1204210
Deposit date:
2021-11-04

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