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Thesis

Control and observation of DNA nanodevices

Abstract:

The uniquely predictable and controllable binding mechanism of DNA strands has been exploited to construct a vast range of synthetic nanodevices, capable of autonomous motion and computation. This thesis proposes novel ideas for the control and observation of such devices. The first of these proposals hinges on introducing mismatched base pairs into toehold-mediated strand displacement – a fundamental primitive in most dynamic DNA devices and reaction networks. Previous findings that such ...

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Institution:
University of Oxford
Research group:
Turberfield Lab
Oxford college:
Merton College
Department:
Mathematical,Physical & Life Sciences Division - Physics - Condensed Matter Physics
Role:
Author

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Role:
Supervisor
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:89e131dd-5179-4ebd-924b-2939f16681d5
Local pid:
ora:9670

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