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Journal article

The clinical features, underlying immunology, and treatment of autoantibody-mediated movement disorders

Abstract:

An increasing number of movement disorders are associated with autoantibodies. Many of these autoantibodies target the extracellular domain of neuronal surface proteins and associate with highly specific phenotypes, suggesting they have pathogenic potential. Below, we describe the phenotypes associated with some of these commoner autoantibody-mediated movement disorders, and outline increasingly well-established mechanisms of autoantibody pathogenicity which include antigen downregulation and...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/mds.27446

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Oxford college:
St Hilda's College
Role:
Author
Publisher:
Wiley Publisher's website
Journal:
Movement Disorders Journal website
Volume:
33
Issue:
9
Pages:
1376-1389
Publication date:
2018-09-14
Acceptance date:
2018-05-02
DOI:
EISSN:
1531-8257
ISSN:
0885-3185
Pmid:
30218501
Source identifiers:
938960
Language:
English
Keywords:
Pubs id:
pubs:938960
UUID:
uuid:860beb7d-ba62-470a-be7d-34fa8570656c
Local pid:
pubs:938960
Deposit date:
2019-02-07

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