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Thesis

Novel radiochemistry for positron emission tomography imaging

Abstract:

This thesis describes the development of novel radiochemistry using fluorine-18 and its subsequent application in conducting Positron Emission Tomography (PET) imaging in vivo. Publication of this work: J. Am. Chem. Soc. 2020, 142 (3), 1180 – 1185.

Chapter 1 introduces PET imaging and fluorine-18 radiochemistry, including an overview of the general considerations made in these areas. An extensive review of the library of radiolabelled fluorinating reagents available and the...

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Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author

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Role:
Supervisor
ORCID:
0000-0001-8638-5308
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Grant:
BBSRCiCase14JP
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Subjects:
Deposit date:
2020-11-01

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