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Can postfertile life stages evolve as an anticancer mechanism?

Abstract:

Why a postfertile stage has evolved in females of some species has puzzled evolutionary biologists for over 50 years. We propose that existing adaptive explanations have underestimated in their formulation an important parameter operating both at the specific and the individual levels: the balance between cancer risks and cancer defenses. During their life, most multicellular organisms naturally accumulate oncogenic processes in their body. In parallel, reproduction, notably the pregnancy pro...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pbio.3000565

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Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Biology Journal website
Volume:
17
Issue:
12
Article number:
e3000565
Publication date:
2019-12-05
Acceptance date:
2019-11-08
DOI:
EISSN:
1545-7885
ISSN:
1544-9173
Source identifiers:
1074465
Keywords:
Pubs id:
pubs:1074465
UUID:
uuid:838f4096-98d1-461e-b837-735417620ff6
Local pid:
pubs:1074465
Deposit date:
2019-11-27

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