Journal article
A Host-Pathogen Interaction Screen Identifies ada2 as a Mediator of Candida glabrata Defenses Against Reactive Oxygen Species
- Abstract:
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Candida glabrata (C. glabrata) forms part of the normal human gut microbiota but can cause life-threatening invasive infections in immune-compromised individuals. C. glabrata displays high resistance to common azole antifungals, which necessitates new treatments. In this investigation, we identified five C. glabrata deletion mutants (∆ada2, ∆bas1, ∆hir3, ∆ino2 and ∆met31) from a library of 196 transcription factor mutants that were unable to grow and activate an immune response in Drosophila ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Funding
Bibliographic Details
- Publisher:
- Genetics Society of America Publisher's website
- Journal:
- G3 Journal website
- Volume:
- 8
- Issue:
- 5
- Pages:
- 1637-1647
- Publication date:
- 2018-03-13
- Acceptance date:
- 2018-03-06
- DOI:
- EISSN:
-
2160-1836
- Pmid:
-
29535147
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:831270
- UUID:
-
uuid:7fca797c-f412-4652-9cda-cf546bf68f31
- Local pid:
- pubs:831270
- Source identifiers:
-
831270
- Deposit date:
- 2019-02-27
Terms of use
- Copyright holder:
- Kounatidis et al
- Copyright date:
- 2018
- Notes:
- © 2018 Kounatidis et al.
- Licence:
- CC Attribution (CC BY)
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