Journal article
Genetic analysis of complex traits in the emerging Collaborative Cross.
- Abstract:
-
The Collaborative Cross (CC) is a mouse recombinant inbred strain panel that is being developed as a resource for mammalian systems genetics. Here we describe an experiment that uses partially inbred CC lines to evaluate the genetic properties and utility of this emerging resource. Genome-wide analysis of the incipient strains reveals high genetic diversity, balanced allele frequencies, and dense, evenly distributed recombination sites-all ideal qualities for a systems genetics resource. We m...
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- Publication status:
- Published
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- Publisher copy:
- 10.1101/gr.111310.110
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Authors
Bibliographic Details
- Journal:
- Genome research
- Volume:
- 21
- Issue:
- 8
- Pages:
- 1213-1222
- Publication date:
- 2011-08-01
- DOI:
- EISSN:
-
1549-5469
- ISSN:
-
1088-9051
- Source identifiers:
-
170294
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:170294
- UUID:
-
uuid:7f941030-5ce3-499b-83b1-7500864e7f29
- Local pid:
- pubs:170294
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2011
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