Thesis
Investigating the role of the endocannabinoid system and gut-microbiome in psychotic and severe mental illness: a focus on negative symptoms
- Abstract:
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Negative symptoms, such as anhedonia and amotivation, represent unmet therapeutic needs and key determinants of functional loss in severe mental illness. Albeit traditionally considered a unique feature of schizophrenia, anhedonia and amotivation manifest outside the psychotic spectrum, where they are equally debilitating and difficult to treat. A number of clinical trials using newly developed compounds or re-repurposing existing drugs have tried to treat negative symptoms without succes...
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Authors
Contributors
+ Lennox, B
Role:
Supervisor
ORCID:
0000-0002-4972-8786
+ Burnet, P
Role:
Supervisor
Funding
+ Medical Research Council
More from this funder
Programme:
Oxford - MRC DTP –St John’s College – Clarendon Studentship
Funder identifier:
http://dx.doi.org/10.13039/501100000265
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- Deposit date:
- 2021-05-14
Related Items
Terms of use
- Copyright holder:
- Minichino, A
- Copyright date:
- 2020
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