Thesis
Development of a novel bead display technology to identify protein ligands: application to identification of viral entry inhibitors and T-cell epitopes
- Abstract:
-
With the continued need for drug discovery and the quest to understand disease and treatment, there remains a requirement for improved methods to study protein-protein interactions and to identify potential drug leads for protein targets.
We sought to develop a new approach to directly link genotype and phenotype to use as a probe for the identification of binding partners of proteins. The method creates millions of water-in-oil emulsions, each of which functions as a micro-environm...
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Authors
Contributors
+ Ogg, G
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Supervisor
Bibliographic Details
- Publication date:
- 2013
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:7ca21487-7e7d-4552-8e16-65ec181c7bcc
- Local pid:
- ora:7990
- Deposit date:
- 2014-02-07
Terms of use
- Copyright holder:
- Huang, L
- Copyright date:
- 2013
- Notes:
- This thesis is not currently available in ORA.
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