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Transgenic Drosophila lines for LexA-dependent gene and growth regulation

Abstract:

Conditional expression of short hairpin RNAs with binary genetic systems is an indispensable tool for studying gene function. Addressing mechanisms underlying cell–cell communication in vivo benefits from simultaneous use of 2 independent gene expression systems. To complement the abundance of existing Gal4/UAS-based resources in Drosophila, we and others have developed LexA/LexAop-based genetic tools. Here, we describe experimental and pedagogical advances that promote...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/g3journal/jkac018

Authors


Publisher:
Oxford University Press
Journal:
G3: Genes | Genomes | Genetics More from this journal
Volume:
12
Issue:
3
Article number:
jkac018
Publication date:
2022-01-19
Acceptance date:
2022-01-05
DOI:
EISSN:
2160-1836
Pmid:
35100369
Language:
English
Keywords:
Pubs id:
1237314
Local pid:
pubs:1237314
Deposit date:
2022-02-26

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