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Journal article

Absence of neuronal autoantibodies in neuropsychiatric systemic lupus erythematosus

Abstract:

This study aimed to characterise both neuronal autoantibodies and levels of interferon α, two proposed causative agents in neuropsychiatric systemic lupus erythematosus (NPSLE). Cerebrospinal fluid (CSF) and plasma from 35 patients with systemic lupus erythematosus (SLE; 15 with NPSLE) showed no antibodies against natively expressed N‐methyl‐D‐aspartate receptors (NMDARs), or the surface of live hippocampal neurons. By comparison to controls (n = 104), patients with SLE had antibodies that bo...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/ana.25908

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Publisher:
Wiley Publisher's website
Journal:
Annals of Neurology Journal website
Volume:
88
Issue:
6
Pages:
1244-1250
Publication date:
2020-09-19
Acceptance date:
2020-09-14
DOI:
EISSN:
1531-8249
ISSN:
0364-5134
Language:
English
Keywords:
Pubs id:
1133250
Local pid:
pubs:1133250
Deposit date:
2020-09-23

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