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Journal article

Characterization and immunogenicity of a Shigella flexneri 2a O-antigen bioconjugate vaccine candidate

Abstract:

Shigellosis remains a major cause of diarrheal disease in developing countries and causes substantial morbidity and mortality in children. Vaccination represents a promising preventive measure to fight the burden of the disease, but despite enormous efforts, an efficacious vaccine is not available to date. The use of an innovative biosynthetic Escherichia coli glycosylation system substantially simplifies the production of a multivalent conjugate vaccine to prevent shigellosis. This bioconjug...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/glycob/cwz044

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Publisher:
Oxford University Press Publisher's website
Journal:
Glycobiology Journal website
Volume:
29
Issue:
9
Pages:
669-680
Publication date:
2019-06-17
Acceptance date:
2019-06-04
DOI:
EISSN:
1460-2423
ISSN:
0959-6658
Pmid:
31206156
Source identifiers:
1020174
Language:
English
Keywords:
Pubs id:
pubs:1020174
UUID:
uuid:765e8562-981b-46c1-b6d4-b3cee3b3a469
Local pid:
pubs:1020174
Deposit date:
2019-06-22

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