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Thesis

Investigating drug and vaccine resistance as a challenge for hepatitis B virus elimination in Africa

Abstract:

Background

The United Nations Sustainable Development Goals set out to eliminate viral hepatitis by the year 2030. However, hepatitis B virus (HBV) drug resistance-associated mutations (RAMs) and/or vaccine escape mutations (VEMs) are potential barriers to the achievement of this target. I have set out to describe the prevalence, distribution and impact of RAMs and VEMs in African populations infected with HBV, with a focus on cohorts in South Africa.

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Oxford college:
Hertford College
Role:
Author
ORCID:
https://orcid.org/0000-0001-8398-0689

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
NDM
Oxford college:
Harris Manchester College
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Examiner
ORCID:
0000-0001-5788-6998
Institution:
Kings College Hospital/University College London Medical School
Role:
Examiner
More from this funder
Programme:
Leverhulme Mandela Rhodes Doctoral Scholarship
Funding agency for:
Mokaya, J
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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