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Thesis

Characterisation of a novel group B oncolytic adenovirus, ColoAd1

Abstract:

Developing high potent oncolytic virus with multimodal antitumour capabilities is crucial for realizing the full potential of oncolytic virotherapy in cancer treatment. ColoAd1 is a novel replicating chimeric group B adenovirus recently bioselected from a large library of recombinant viruse. This thesis aims at evaluating the oncolysis ability of ColoAd1, characterization of its cellular activities and the corresponding responses from host tumour cells, elucidating the killing mechanism a...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Oxford college:
Wolfson College
Role:
Author

Contributors

Division:
MSD
Department:
Pharmacology
Role:
Supervisor
Publication date:
2011
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:70348cdc-13a4-473e-b4b6-88f04b1c407c
Local pid:
ora:6052
Deposit date:
2012-02-06

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