Journal article
Viral vectors expressing group B meningococcal outer membrane proteins induce strong antibody responses but fail to induce functional bactericidal activity
- Abstract:
-
Objective
Adenoviral vectored vaccines, with the appropriate gene insert, induce cellular and antibody responses against viruses, parasites and intracellular pathogens such as Mycobacterium tuberculosis. Here we explored their capacity to induce functional antibody responses to meningococcal transmembrane outer membrane proteins.Methods
Vectors expressing porin A and ferric enterobactin receptor A antigens were generated, and their immunogenic... Expand abstract
- Publication status:
- In press
- Peer review status:
- Peer reviewed
Actions
Authors
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Journal of Infection Journal website
- Volume:
- 84
- Issue:
- 5
- Pages:
- 658-667
- Publication date:
- 2022-03-01
- Acceptance date:
- 2022-02-27
- DOI:
- EISSN:
-
1532-2742
- ISSN:
-
0163-4453
- Pmid:
-
35245584
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1243402
- Local pid:
- pubs:1243402
- Deposit date:
- 2022-03-28
Terms of use
- Copyright holder:
- Crown Copyright
- Copyright date:
- 2022
- Rights statement:
- Crown Copyright © 2022 Published by Elsevier Ltd on behalf of The British Infection Association. This is an open access article under a Creative Commons license.
- Licence:
- CC Attribution (CC BY)
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