Thesis
Single-cell characterisation of T lymphocyte immune responses in spondyloarthropathy
- Abstract:
-
The spondyloarthropathies (SpA) are a collection of inflammatory disorders of undetermined etiology affecting the joints and connective tissues, however existing evidence suggests a role for the microbiome, CD4 and CD8 T cells in disease pathogenesis.
A CD154 activation based functional assay was first used to quantify and characterise CD4+ memory T cell populations reactive to a panel of 13 microbes found at mucosal barrier sites, predominantly gut bacteria. Peripheral blood monon...
Expand abstract
Actions
Authors
Contributors
+ Bowness, P
Role:
Supervisor
+ Powrie, F
Role:
Supervisor
+ Klenerman, P
Role:
Examiner
+ Eidsmo, L
Role:
Examiner
Funding
+ Kennedy Institute of Rheumatology
More from this funder
Programme:
Kennedy Institute Prize Studentship
Funding agency for:
Penkava, F
Grant:
AZR00280 - HF00.05
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- Deposit date:
- 2021-09-09
Related Items
Terms of use
- Copyright holder:
- Penkava, F
- Copyright date:
- 2019
If you are the owner of this record, you can report an update to it here: Report update to this record