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Stage-specific sampling by pattern recognition receptors during Candida albicans phagocytosis.

Abstract:

Candida albicans is a medically important pathogen, and recognition by innate immune cells is critical for its clearance. Although a number of pattern recognition receptors have been shown to be involved in recognition and phagocytosis of this fungus, the relative role of these receptors has not been formally examined. In this paper, we have investigated the contribution of the mannose receptor, Dectin-1, and complement receptor 3; and we have demonstrated that Dectin-1 is the main non-opsoni...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.ppat.1000218

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Institution:
University of Oxford
Role:
Author
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Institution:
University of Oxford
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Author
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Institution:
University of Oxford
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Author
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Institution:
University of Oxford
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Author
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Funding agency for:
Taylor, P
Grant:
G0601617
Wellcome Trust More from this funder
Oxford University More from this funder
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Publisher:
Public Library of Science Publisher's website
Journal:
PLoS pathogens Journal website
Volume:
4
Issue:
11
Pages:
e1000218
Publication date:
2008-11-01
DOI:
EISSN:
1553-7374
ISSN:
1553-7366
Source identifiers:
4608
Language:
English
Keywords:
Pubs id:
pubs:4608
UUID:
uuid:6bec4e0d-083d-41db-95c5-9d76cfee9779
Local pid:
pubs:4608
Deposit date:
2012-12-19

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