Thesis icon

Thesis

Membrane protein mechanotransduction: computational studies and analytics development

Abstract:

Membrane protein mechanotransduction is the altered function of an integral membrane protein in response to mechanical force. Such mechanosensors are found in all kingdoms of life, and increasing numbers of membrane proteins have been found to exhibit mechanosensitivity. How they mechanotransduce is an active research area and the topic of this thesis.

The methodology employed is classical molecular dynamics (MD) simulations. MD systems are complex, and two programs were developed t...

Expand abstract

Actions


Access Document


Files:

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Research group:
Structural Bioinformatics and Computational Biochemistry
Oxford college:
St Cross College
Role:
Author
More by this author
Division:
MSD
Department:
Biochemistry
Role:
Author

Contributors

Role:
Supervisor
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP