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Risk of gastrointestinal bleeding in patients undergoing total hip or knee replacement compared with matched controls: A nationwide cohort study

Abstract:

Objectives: Gastrointestinal (GI) bleeding may impose a serious threat in patients undergoing total hip or knee replacement (THR/TKR). The objectives of this study are to evaluate the timing of GI bleeding following THR/TKR and to determine the effect modification by proton pump inhibitor (PPI) use.Methods: In a nationwide Danish cohort study, we selected all patients with a primary THR/TKR between 1998 and 2007 (n=95,115). Three control subjects without THR/TKR were matched by age, sex, and ...

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Publisher copy:
10.1038/ajg.2013.108

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
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Journal:
American Journal of Gastroenterology
Volume:
108
Issue:
8
Pages:
1277-1285
Publication date:
2013-08-01
DOI:
EISSN:
1572-0241
ISSN:
0002-9270
Source identifiers:
419350
Language:
English
Pubs id:
pubs:419350
UUID:
uuid:676c3ca7-27a5-44dd-ae02-17bdafb1ca67
Local pid:
pubs:419350
Deposit date:
2013-11-17

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