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Wac: a new Augmin subunit required for chromosome alignment but not for acentrosomal microtubule assembly in female meiosis

Abstract:

The bipolar spindle forms without centrosomes naturally in female meiosis and by experimental manipulation in mitosis. Augmin is a recently discovered protein complex required for centrosome-independent microtubule generation within the spindle in Drosophila melanogaster cultured cells. Five subunits of Augmin have been identified so far, but neither their organization within the complex nor their role in developing organisms is known. In this study, we report a new Augmin subunit...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1083/jcb.200811102

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Institution:
"University of Edinburgh", "University of Coimbra, Portugal"
Department:
Doctoral Programme in Experimental Biology and Biomedicine,Center for Neuroscience and Cell Biology
Role:
Author
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Institution:
University of Oxford
Department:
Mathematical,Physical & Life Sciences Division - Zoology
Role:
Author
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Institution:
"University of Edinburgh"
Department:
Wellcome Trust Centre for Cell Biology
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Mathematical,Physical & Life Sciences Division - Zoology
Role:
Author
More by this author
Institution:
"University of Edinburgh"
Department:
Wellcome Trust Centre for Cell Biology
Role:
Author
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Funding agency for:
Ana M. Meireles
Wellcome Trust More from this funder
Publisher:
Rockefeller University Press Publisher's website
Journal:
Journal of Cell Biology Journal website
Volume:
184
Issue:
6
Pages:
777-784
Publication date:
2009-03-05
DOI:
EISSN:
1540-8140
ISSN:
0021-9525
URN:
uuid:675cd9cf-e0ab-4691-a5f2-0d47e430722a
Local pid:
ora:7361

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