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Journal article

The effect of camicinal (GSK962040), a motilin agonist, on gastric emptying and glucose absorption in feed-intolerant critically ill patients: a randomized, blinded, placebo-controlled, clinical trial

Abstract:

Background The promotility agents currently available to treat gastroparesis and feed intolerance in the critically ill are limited by adverse effects. The aim of this study was to assess the pharmacodynamic effects and pharmacokinetics of single doses of the novel gastric promotility agent motilin agonist camicinal (GSK962040) in critically ill feed-intolerant patients.

Methods A prospective, randomized, double-blind, parallel-group, placebo-contro...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s13054-016-1420-4

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Publisher:
BioMed Central Publisher's website
Journal:
Critical Care Journal website
Volume:
20
Issue:
1
Pages:
232
Publication date:
2016-08-01
Acceptance date:
2016-07-20
DOI:
EISSN:
1466-609X
ISSN:
1364-8535
Pmid:
27476581
Source identifiers:
1033404
Language:
English
Keywords:
Pubs id:
pubs:1033404
UUID:
uuid:667722b1-73f4-44d4-8100-6083b20868af
Local pid:
pubs:1033404
Deposit date:
2019-07-18

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