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How to tackle challenging ChIP-Seq, with long-range cross-linking, using ATRX as an example
- Abstract:
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Chromatin immunoprecipitation coupled with high-throughput, next-generation DNA sequencing (ChIP-seq) has enabled researchers to establish the genome-wide patterns of chromatin modifications and binding of chromatin-associated proteins. Well-established protocols produce robust ChIP-seq data for many proteins by sequencing the DNA obtained following immunoprecipitation of fragmented chromatin using a wide range of specific antibodies. In general, the quality of these data mainly depends on th...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Accepted manuscript, pdf, 618.8KB)
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- Publisher copy:
- 10.1007/978-1-4939-8663-7_6
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Funding
Bibliographic Details
- Publisher:
- Springer Publisher's website
- Pages:
- 105-130
- Series:
- Methods in Molecular Biology
- Host title:
- Methods in Molecular Biology
- Publication date:
- 2018-08-03
- Acceptance date:
- 2018-06-05
- DOI:
- EISSN:
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1940-6029
- ISSN:
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1064-3745
- Pmid:
-
30073524
- Source identifiers:
-
905109
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:905109
- UUID:
-
uuid:64a219a8-1fcd-4f55-ad54-cc862764f2aa
- Local pid:
- pubs:905109
- Deposit date:
- 2018-12-04
Terms of use
- Copyright holder:
- Springer Science+Business Media, LLC
- Copyright date:
- 2018
- Notes:
- © Springer Science+Business Media, LLC, part of Springer Nature 2018. This is the accepted manuscript version of the article. The final version is available online from Springer at: https://doi.org/10.1007/978-1-4939-8663-7_6
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