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The association of weight loss with changes in the gut microbiota diversity, composition, and intestinal permeability: a systematic review and meta-analysis

Abstract:

The gut microbiome may be a mediator between obesity and health outcomes. However, it is unclear how intentional weight loss changes the gut microbiota and intestinal permeability. We aimed to systematically review and quantify this association. We searched Medline, Embase, CINAHL, Cochrane databases, and trial registries until June 2020 (PROSPERO: CRD42020205292). We included trials of weight loss interventions (energy-restricted diets, pharmacotherapy, bariatric surgery) reporting on the mi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1080/19490976.2021.2020068

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
ORCID:
0000-0002-1955-7234
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Oxford college:
Hertford College
Role:
Author
ORCID:
0000-0001-9190-2920
More by this author
Role:
Author
ORCID:
0000-0002-7650-0963
Publisher:
Taylor and Francis Publisher's website
Journal:
Gut Microbes Journal website
Volume:
14
Issue:
1
Article number:
e2020068
Publication date:
2022-01-18
Acceptance date:
2021-12-13
DOI:
EISSN:
1949-0984
ISSN:
1949-0976
Language:
English
Keywords:
Pubs id:
1232957
Local pid:
pubs:1232957
Deposit date:
2022-01-18

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