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Thesis

Probing the molecular basis of melanopsin induced light sensitivity

Abstract:

It has been demonstrated that retinal photoreception among mammals extends beyond rods and cones to include a small number of intrinsically photosensitive retinal ganglion cells (pRGCs), which are capable of responding to light due to expression of the melanopsin (OPN4) photopigment. OPN4 may have therapeutic potential if ectopically expressed in the degenerate retina in cases where photoreceptors are lost, but the other molecules involved in this light induced transducti...

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Research group:
Nuffield Laboratory of Neurosciences
Oxford college:
Green Templeton College
Role:
Author

Contributors

Division:
MSD
Department:
Clinical Neurosciences
Role:
Supervisor
Publication date:
2012
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
University of Oxford
UUID:
uuid:631deeeb-90c0-4e90-b24e-f03e1b318d8b
Local pid:
ora:9063

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