Journal article
Prisoners of war — host adaptation and its constraints on virus evolution
- Abstract:
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Recent discoveries of contemporary genotypes of hepatitis B virus and parvovirus B19 in ancient human remains demonstrate that little genetic change has occurred in these viruses over 4,500–6,000 years. Endogenous viral elements in host genomes provide separate evidence that viruses similar to many major contemporary groups circulated 100 million years ago or earlier. In this Opinion article, we argue that the extraordinary conservation of virus genome sequences is best explained by a niche-f...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Accepted manuscript, pdf, 1.7MB)
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- Publisher copy:
- 10.1038/s41579-018-0120-2
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Authors
Bibliographic Details
- Publisher:
- Springer Nature Publisher's website
- Journal:
- Nature Reviews Microbiology Journal website
- Volume:
- 17
- Pages:
- 321–328
- Publication date:
- 2018-12-05
- DOI:
- EISSN:
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1740-1534
- ISSN:
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1740-1526
- Pmid:
-
30518814
- Source identifiers:
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952107
Item Description
- Language:
- English
- Pubs id:
-
pubs:952107
- UUID:
-
uuid:62d6a53e-5281-4f42-8483-87e86b9965a4
- Local pid:
- pubs:952107
- Deposit date:
- 2019-02-05
Terms of use
- Copyright holder:
- Simmonds et al
- Copyright date:
- 2018
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from Springer Nature at: https://doi.org/10.1038/s41579-018-0120-2
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