Journal article
Mitophagy plays a central role in mitochondrial ageing
- Abstract:
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The mechanisms underlying ageing have been discussed for decades, and advances in molecular and cell biology of the last three decades have accelerated research in this area. Over this period, it has become clear that mitochondrial function, which plays a major role in many cellular pathways from ATP production to nuclear gene expression and epigenetics alterations, declines with age. The emerging concepts suggest novel mechanisms, involving mtDNA quality, mitochondrial dynamics or mitochondr...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 891.5KB)
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- Publisher copy:
- 10.1007/s00335-016-9651-x
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Authors
Funding
Angus Memorial Mitochondrial Fund
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Lily Foundation
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Bibliographic Details
- Publisher:
- Springer Verlag Publisher's website
- Journal:
- Mammalian Genome Journal website
- Issue:
- 7-8
- Publication date:
- 2016-06-28
- Acceptance date:
- 2016-05-24
- DOI:
- ISSN:
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1432-1777 and 0938-8990
- Source identifiers:
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631063
Item Description
Terms of use
- Copyright holder:
- Diot, Morten and Poulton
- Copyright date:
- 2016
- Notes:
- The Author(s) 2016. This article is published with open access at Springerlink.com. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License.
- Licence:
- CC Attribution (CC BY)
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