Thesis
Innate immune pathways controlling IL-1beta production and adjuvant-induced T helper 17 cell differentiation
- Abstract:
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Although adjuvants are critical vaccine components, their modes of action are poorly understood. This has hampered the development of novel adjuvants, and as a result there are very few approved for clinical use. Moreover, none of the clinically-approved adjuvants are able to induce T helper 17 (Th17) CD4+ T cell responses. Th17 cells play important roles in host defense against extracellular bacteria, fungi, and some intracellular pathogens, so understanding how to produce Th17...
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Bibliographic Details
- Publication date:
- 2011
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
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uuid:610114e6-c1ac-46c2-af4b-4a69659ce8b8
- Deposit date:
- 2016-11-15
Terms of use
- Copyright holder:
- Shenderov, K
- Copyright date:
- 2012
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