Causal effects of gallstone disease on risk of gastrointestinal cancer in Chinese
Background: Gallstone disease (GSD) is associated with a higher risk of gastrointestinal (GI) cancer. However, it is unclear whether the associations are causal.
Methods: The prospective China Kadoorie Biobank (CKB) recorded 17,598 cases of GI cancer among 510,137 participants without cancer at baseline during 10 years of follow-up. Cox regression was used to estimate hazard ratios (HRs) for specific cancer by GSD status and duration. Mendelian ran...Expand abstract
- Publication status:
- Peer review status:
- Peer reviewed
(Accepted manuscript, 661.6KB)
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- Copyright holder:
- Pang et al.
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- © The Author(s), under exclusive licence to Cancer Research UK 2021
- This is the accepted manuscript version of the article. The final version is available online from Springer Nature at: https://doi.org/10.1038/s41416-021-01325-w
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