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Journal article

Causal effects of gallstone disease on risk of gastrointestinal cancer in Chinese

Abstract:

Background: Gallstone disease (GSD) is associated with a higher risk of gastrointestinal (GI) cancer. However, it is unclear whether the associations are causal.

Methods: The prospective China Kadoorie Biobank (CKB) recorded 17,598 cases of GI cancer among 510,137 participants without cancer at baseline during 10 years of follow-up. Cox regression was used to estimate hazard ratios (HRs) for specific cancer by GSD status and duration. Mendelian ran...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41416-021-01325-w

Authors


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Institution:
University of Oxford
Division:
MSD
Sub department:
Clinical Trial Service Unit
Oxford college:
Green Templeton; GREEN TEMPLETON COLLEGE
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Sub department:
Clinical Trial Service Unit
Role:
Author
ORCID:
0000-0002-3981-3418
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Publisher:
Springer Nature Publisher's website
Journal:
British Journal of Cancer Journal website
Volume:
124
Issue:
11
Pages:
1864-1872
Publication date:
2021-03-26
Acceptance date:
2021-02-19
DOI:
EISSN:
1532-1827
ISSN:
0007-0920
Pmid:
33772150
Language:
English
Keywords:
Pubs id:
1169602
Local pid:
pubs:1169602
Deposit date:
2021-07-27

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