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Low salivary cortisol levels in patients with rheumatoid arthritis exposed to oral glucocorticoids: a cross-sectional study set within UK electronic health records

Abstract:

Background Glucocorticoids (GCs) suppress endogenous cortisol levels which can lead to adrenal insufficiency (AI). The frequency of GC-induced AI remains unclear. In this cross-sectional study, low morning salivary cortisol (MSC) levels were used as a measure of adrenal function. The study aim was to investigate the prevalence of low MSC in patients with rheumatoid arthritis (RA) currently and formerly exposed to oral GCs, and the association with potential risk factors.

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1136/rmdopen-2018-000700

Authors


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Role:
Author
ORCID:
0000-0002-0147-0712
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Sub department:
OCDEM
Department:
Unknown
Role:
Author
ORCID:
0000-0002-4739-6773
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Role:
Author
ORCID:
0000-0001-9363-742X
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Role:
Author
ORCID:
0000-0001-5881-4857
Publisher:
BMJ Publishing Group Publisher's website
Journal:
RMD Open Journal website
Volume:
4
Issue:
2
Article number:
e000700
Publication date:
2018-10-01
Acceptance date:
2018-07-18
DOI:
EISSN:
2056-5933
Pmid:
30305930
Source identifiers:
930691
Language:
English
Keywords:
Pubs id:
pubs:930691
UUID:
uuid:5d87b749-2247-404f-b891-05d4fc78ab05
Local pid:
pubs:930691
Deposit date:
2019-02-08

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