Journal article
Immunogenicity and protective efficacy of a live attenuated H5N1 vaccine in nonhuman primates.
- Abstract:
-
The continued spread of highly pathogenic H5N1 influenza viruses among poultry and wild birds, together with the emergence of drug-resistant variants and the possibility of human-to-human transmission, has spurred attempts to develop an effective vaccine. Inactivated subvirion or whole-virion H5N1 vaccines have shown promising immunogenicity in clinical trials, but their ability to elicit protective immunity in unprimed human populations remains unknown. A cold-adapted, live attenuated vaccin...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
-
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(Version of record, pdf, 627.1KB)
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- Publisher copy:
- 10.1371/journal.ppat.1000409
Authors
Funding
United States Public Health Service
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National Institute of Allergy and Infectious Disease
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Ministry of SCience of Japan
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Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLOS PATHOGENS Journal website
- Volume:
- 5
- Issue:
- 5
- Pages:
- e1000409
- Publication date:
- 2009-05-01
- DOI:
- EISSN:
-
1553-7374
- ISSN:
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1553-7366
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:5d85f545-29f8-48ea-af88-dce89397147d
- Local pid:
- pubs:95801
- Source identifiers:
-
95801
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Fan et al
- Copyright date:
- 2009
- Notes:
- © 2009 Fan et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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