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Protective effect of antirheumatic drugs on dementia in rheumatoid arthritis patients

Abstract:

INTRODUCTION Rheumatoid Arthritis is a systemic inflammatory disease and classical disease-modifying anti-rheumatic drugs (cDMARDs) have proven efficacy. It is unknown what impact cDMARDs might have on dementia as an outcome.

METHODS Incident diagnoses of Rheumatoid Arthritis in persons over 18 years from 1995 to 2011 were identified from the UK Clinical Practice Research Datalink. 3,876 cDMARD users were propensity score matched to 1,938 non-users, on a wide range of confounders....

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
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Publisher copy:
10.1016/j.trci.2017.10.002

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
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Roche-Chugai More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Alzheimer's & Dementia: Translational Research & Clinical Interventions Journal website
Volume:
3
Issue:
4
Pages:
612-621
Publication date:
2017-11-09
Acceptance date:
2017-10-11
DOI:
EISSN:
2352-8737
Pubs id:
pubs:735197
URN:
uri:5d2e68ef-cec6-4c09-bd2f-e1cfdf1ffcc0
UUID:
uuid:5d2e68ef-cec6-4c09-bd2f-e1cfdf1ffcc0
Local pid:
pubs:735197

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