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Constructing human atrial electrophysiological models mimicking a patient-specific cell group

Abstract:

Patient-specific modelling aims to produce computational models of human physiology tailored to a specific patient. In line with this, we construct multiple human atrial electrophysiological models mimicking the behaviour of single atrial myocytes extracted from a homogeneous patient group. We study cells with the action potential duration being 2-3 times lower than in human atrial electrophysiological models. Assuming such a difference can be rationalized by altering the values of ionic cond...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MPLS
Department:
Computer Science
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
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Institution:
University of Oxford
Oxford college:
St Cross College
Role:
Author
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Funding agency for:
Bueno-Orovio, A
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Funding agency for:
Rodriguez, B
Publisher:
Institute of Electrical and Electronics Engineers Publisher's website
Journal:
Computing in Cardiology 2014, Cambridge, MA, USA 7-10 Sept. 2014, 41, 761-764 Journal website
Volume:
41
Pages:
761-764
Host title:
Computing in Cardiology 2014, Cambridge, MA, USA 7-10 Sept. 2014
Publication date:
2015-02-19
EISSN:
2325-8853
ISSN:
0276-6574
Source identifiers:
531101
ISBN:
9781479943463
Pubs id:
pubs:531101
UUID:
uuid:5b5ad72d-4805-4aaa-9650-bc9cc2665780
Local pid:
pubs:531101
Deposit date:
2017-07-03

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