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Thesis

The identification and analysis of molecular biomarkers in the p53 tumour suppressor pathway that affect cancer progression in humans

Abstract:

The tumour suppressor p53 is at the centre of the signalling pathway that controls cellular processes crucial in tumourogenesis, cancer progression and tumour clearance. Alterations in the p53 pathway that lead to cancer progression can be good candidates for molecular biomarkers that would assist in the identification of patients with different prognoses, but also serve as good predictors of appropriate targeted therapies.

Patient cohorts and cancer cell panels are utilised to seek...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Oxford college:
Wolfson College
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Publication date:
2013
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:5a76b7ca-22f6-4f49-b715-5ad43f916984
Local pid:
ora:10437
Deposit date:
2015-03-04

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