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Association of heart rate and diabetes among 0.5 million adults in the China Kadoorie biobank: Results from observational and Mendelian randomization analyses

Abstract:

Background and aims

Observational studies have associated resting heart rate with incident diabetes. Whether the associations are causal remains unclear. We aimed to examine the shape and strength of the associations and assessed the causal relevance of such associations in Chinese adults.

Methods and results

The China Kadoorie Biobank enrolled 512,891 adults in China. Cox proportional hazard regression models was conducted to estimate hazard ra... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.numecd.2021.04.015

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Publisher:
Elsevier Publisher's website
Journal:
Nutrition, Metabolism and Cardiovascular Diseases Journal website
Volume:
31
Issue:
8
Pages:
2328-2337
Publication date:
2021-04-26
Acceptance date:
2021-04-16
DOI:
EISSN:
1590-3729
ISSN:
0939-4753
Pmid:
34052074
Language:
English
Keywords:
Pubs id:
1179858
Local pid:
pubs:1179858
Deposit date:
2021-06-16

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