Journal article
A phase I trial evaluating the safety and immunogenicity of a candidate tuberculosis vaccination regimen, ChAdOx1 85A prime - MVA85A boost in healthy UK adults
- Abstract:
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BACKGROUND: This phase I trial evaluated the safety and immunogenicity of a candidate tuberculosis vaccination regimen, ChAdOx1 85A prime-MVA85A boost, previously demonstrated to be protective in animal studies, in healthy UK adults.
METHODS: We enrolled 42 healthy, BCG-vaccinated adults into 4 groups: low dose Starter Group (n = 6; ChAdOx1 85A alone), high dose groups; Group A (n = 12; ChAdOx1 85A), Group B (n = 12; ChAdOx1 85A prime - MVA85A boost...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, pdf, 2.8MB)
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(Version of record, 2.7MB)
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- Publisher copy:
- 10.1016/j.vaccine.2019.10.102
Authors
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Vaccine Journal website
- Volume:
- 38
- Issue:
- 2020
- Pages:
- 779-789
- Publication date:
- 2019-11-15
- Acceptance date:
- 2019-10-31
- DOI:
- EISSN:
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1873-2518
- ISSN:
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0264-410X
- Pmid:
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31735500
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:1073096
- UUID:
-
uuid:5869a47f-58c4-4222-b1e2-beefd7e168f6
- Local pid:
- pubs:1073096
- Source identifiers:
-
1073096
- Deposit date:
- 2019-11-26
Terms of use
- Copyright holder:
- Elsevier
- Copyright date:
- 2019
- Rights statement:
- © 2019 Published by Elsevier Ltd. This article is open access, made accessible by creative commons (https://creativecommons.org/licenses/by/4.0)
- Licence:
- CC Attribution (CC BY)
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