Journal article
Homozygosity and risk of childhood death due to invasive bacterial disease
- Abstract:
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Background: Genetic heterozygosity is increasingly being shown to be a key predictor of fitness in natural populations, both through inbreeding depression, inbred individuals having low heterozygosity, and also through chance linkage between a marker and a gene under balancing selection. One important component of fitness that is often highlighted is resistance to parasites and other pathogens. However, the significance of equivalent loci in human populations remains unclear. Consequently, we...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, doc, 69.0KB)
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(Version of record, pdf, 301.8KB)
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- Publisher copy:
- 10.1186/1471-2350-10-55
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Authors
Funding
Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- BMC Medical Genetics Journal website
- Volume:
- 10
- Article number:
- 55
- Publication date:
- 2009-06-01
- DOI:
- ISSN:
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1471-2350
Item Description
- Language:
- English
- Subjects:
- UUID:
-
uuid:575b1e31-54bc-4a88-b9ad-b376d4859e1a
- Local pid:
- ora:3082
- Deposit date:
- 2009-11-25
Related Items
Terms of use
- Copyright holder:
- Lyons et al
- Copyright date:
- 2009
- Notes:
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Citation: Lyons, E. J. et al. (2009). 'Homozygosity and risk of childhood death due to invasive bacterial disease', BMC Medical Genetics, 10:55. [This article is available from: http://www.biomedcentral.com/1471-2350/10/55]. © 2009 Lyons et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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