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Journal article

Tocilizumab-associated multifocal cerebral thrombotic microangiopathy

Abstract:

Tocilizumab is a humanized monoclonal antibody that targets the interleukin-6 receptor (IL-6-R). It is approved for use in moderate to severe refractory rheumatoid arthritis and more recently has been found to be effective in treating neuromyelitis optica.1 Common side effects include raised hepatic transaminases, gastroenteritis, infections, and hypertension. Neurologic side effects have been described in 2 single case reports, which were confounded by the concomitant use of other antirheuma...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1212/CPJ.0000000000000220

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Institution:
University of Oxford
Oxford college:
St Hilda's College
Role:
Author
Publisher:
American Academy of Neurology Publisher's website
Journal:
Neurology. Clinical practice Journal website
Volume:
6
Issue:
3
Pages:
e24-e26
Publication date:
2016-06-27
DOI:
EISSN:
2163-0933
ISSN:
2163-0402
Pmid:
27347443
Source identifiers:
630933
Language:
English
Keywords:
Pubs id:
pubs:630933
UUID:
uuid:56d64642-1b44-41bf-bed3-0fc5668648bb
Local pid:
pubs:630933
Deposit date:
2016-12-09

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