Common genetic variation indicates separate causes for periventricular and deep white matter hyperintensities
Background and Purpose:
Periventricular white matter hyperintensities (WMH; PVWMH) and deep WMH (DWMH) are regional classifications of WMH and reflect proposed differences in cause. In the first study, to date, we undertook genome-wide association analyses of DWMH and PVWMH to show that these phenotypes have different genetic underpinnings.
Participants were aged 45 years and older, free of stroke and dementia. We conduct...
- Publication status:
- Peer review status:
- Peer reviewed
(Accepted manuscript, 790.2KB)
- Publisher copy:
- Copyright holder:
- American Heart Association
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- Rights statement:
- © 2020 American Heart Association, Inc.
- This is the accepted manuscript version of the article. The final version is available online from the American Heart Association at: https://doi.org/10.1161/STROKEAHA.119.027544
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