Journal article
Heterogeneity in myeloproliferative neoplasms: causes and consequences
- Abstract:
-
Myeloproliferative neoplasms (MPNs) are haematopoietic stem cell-derived clonal disorders characterised by proliferation of some or all myeloid lineages, depending on the subtype. MPNs are classically categorized into three disease subgroups; essential thrombocythaemia (ET), polycythaemia vera (PV) and primary myelofibrosis (PMF). The majority (>85%) of patients carry a disease-initiating or driver mutation, the most prevalent occurring in the janus kinase 2 gene (JAK2 V617F), followed by ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1016/j.jbior.2018.11.007
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Authors
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Advances in Biological Regulation Journal website
- Volume:
- 71
- Pages:
- 55-68
- Publication date:
- 2018-11-22
- Acceptance date:
- 2018-11-20
- DOI:
- EISSN:
-
2212-4934
- ISSN:
-
2212-4926
- Pmid:
-
30528537
- Source identifiers:
-
953469
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:953469
- UUID:
-
uuid:569433d5-bd9a-4e29-afda-759c0cd6d54e
- Local pid:
- pubs:953469
- Deposit date:
- 2019-01-30
Terms of use
- Copyright holder:
- Elsevier Ltd
- Copyright date:
- 2018
- Notes:
- © 2018 Elsevier Ltd. All rights reserved.
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