Thesis
The role of autophagy in mature adipocytes during homeostasis and intestinal inflammation
- Abstract:
-
Autophagy is an evolutionary conserved lysosomal degradation pathway, which can control cell-intrinsic functions such as di erentiation and cellular metabolism. The cell-intrinsic role of autophagy is of particular importance to immune cells, but autophagy also has a cell-extrinsic role in the tumour environment. It remains unclear whether autophagy in the tissue environment can alter immune responses. The release of free fatty acids (FFA) from adipocytes in times of high energy demands (e...
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Authors
Contributors
+ Simon, A
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Oxford college:
Wolfson College
Role:
Supervisor
+ Edwards, C
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Oxford college:
St Edmund Hall
Role:
Supervisor
+ Friedrich, M
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Oxford college:
Wolfson College
Role:
Supervisor
Funding
+ Wellcome Trust
More from this funder
Funder identifier:
http://dx.doi.org/10.13039/100010269
Funding agency for:
Richter, FC
Grant:
203803/Z16/Z
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- Deposit date:
- 2022-04-19
Related Items
Terms of use
- Copyright holder:
- Richter, FC
- Copyright date:
- 2021
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