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Multiple inhibitory factors act in the late phase of HIV-1 replication: A systematic review of the literature

Abstract:

The use of lentiviral vectors for therapeutic purposes has shown promising results in clinical trials. The ability to produce a clinical-grade vector at high yields remains a critical issue. One possible obstacle could be cellular factors known to inhibit human immunodeficiency virus (HIV). To date, five HIV restriction factors have been identified, although it is likely that more factors are involved in the complex HIV-cell interaction. Inhibitory factors that have an adverse effect but do n...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1128/mmbr.00051-17

Authors


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Role:
Author
ORCID:
0000-0003-3454-5781
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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Clinical Laboratory Sciences
Oxford college:
University College
Role:
Author
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM; RDM Clinical Laboratory Sciences
Role:
Author
Cystic Fibrosis Trust More from this funder
Publisher:
American Society for Microbiology Publisher's website
Journal:
Microbiology and Molecular Biology Reviews Journal website
Volume:
82
Issue:
1
Pages:
e00051-17
Publication date:
2018-01-10
Acceptance date:
2018-01-03
DOI:
EISSN:
1098-5557
ISSN:
1092-2172
Pmid:
29321222
Source identifiers:
821493
Language:
English
Keywords:
Pubs id:
pubs:821493
UUID:
uuid:5504b3f2-d008-46cc-98cf-b3fa436d0231
Local pid:
pubs:821493
Deposit date:
2018-08-06

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