Thesis
Exploring the roles of LIM domain binding proteins in zebrafish development
- Abstract:
-
As some of the most important and widely utilised intercellular signalling molecules, transforming growth factor βs (TGFβs) play critical roles in normal development and in human disease. Establishing appropriate levels of signalling involves positive and negative feedback, driven by the same signal transduction components, but whether or how the two are distinguished has not previously been understood. Here we show that LIM domain binding proteins (Ldbs) drive the Smad6/7-mediated negativ...
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Bibliographic Details
- Publication date:
- 2014
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:54f520f6-170a-480a-a195-1a0739055031
- Local pid:
- ora:9616
- Deposit date:
- 2014-12-17
Terms of use
- Copyright holder:
- Gu, W
- Copyright date:
- 2014
- Notes:
- This thesis is not currently available on ORA.
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