Thesis
A novel role for Atmin as a transcription factor controlling ciliogenesis
- Abstract:
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Cilia are cellular organelles involved in processing components of the hedgehog (hh) signalling pathway and determining left-right (L-R) axis formation in the embryo. An embryonic lethal mouse mutant, called gasping 6 (gpg6), was identified that demonstrated morphological and molecular defects associated with L-R development and hh signalling. gpg6 mutant embryos also demonstrate abnormally short cilia, which was hypothesised to be the primary morphological defec...
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Funding
Bibliographic Details
- Publication date:
- 2011
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
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uuid:52de0cea-164d-4ca3-8ac1-0b2cda1ba4b2
- Local pid:
- ora:11956
- Deposit date:
- 2015-07-28
Terms of use
- Copyright holder:
- Stevens, J
- Copyright date:
- 2011
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