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Journal article

Transfusion volume for children with severe anemia in Africa

Abstract:

BACKGROUND

Severe anemia (hemoglobin level, ≺6 g per deciliter) is a leading cause of hospital admission and death in children in sub-Saharan Africa. The World Health Organization recommends transfusion of 20 ml of whole-blood equivalent per kilogram of body weight for anemia, regardless of hemoglobin level.


METHODS

In this factorial, open-label trial, we randomly assigned Ugandan and Malawian children 2 months to 12 years of age with a hemoglobin level of less t...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1056/NEJMoa1900100

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Funding agency for:
Walker, AS
Grant:
Senior Investigator
Publisher:
Massachusetts Medical Society Publisher's website
Journal:
New England Journal of Medicine Journal website
Volume:
381
Issue:
5
Pages:
420-431
Publication date:
2019-08-01
Acceptance date:
2019-06-18
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
Source identifiers:
1016623
Pubs id:
pubs:1016623
UUID:
uuid:51ff33f2-6d49-477f-9b64-8c7828515c14
Local pid:
pubs:1016623
Deposit date:
2019-06-18

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