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The influence of the descending pain modulatory system on infant pain-related brain activity

Abstract:

The descending pain modulatory system (DPMS) constitutes a network of widely distributed brain regions whose integrated function is essential for effective modulation of sensory input to the central nervous system and behavioural responses to pain. Animal studies demonstrate that young rodents have an immature DPMS, but comparable studies have not been conducted in human infants. In Goksan et al. 2015 we used functional MRI (fMRI) to show that pain-related brain activity in newborn infants is...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.7554/eLife.37125.001

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Paediatrics
Role:
Author
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Publisher:
eLife Sciences Publications Publisher's website
Journal:
eLife Journal website
Volume:
7
Pages:
e37125
Publication date:
2018-09-11
Acceptance date:
2018-08-15
DOI:
EISSN:
2050-084X
Source identifiers:
910895
Pubs id:
pubs:910895
UUID:
uuid:509cd861-e79a-4622-846b-6c296c77ca42
Local pid:
pubs:910895
Deposit date:
2018-08-29

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