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Journal article : Review

Transcriptional regulation of neutrophil differentiation and function during inflammation

Abstract:

Neutrophils are the most abundant leukocytes in innate immunity where they elicit powerful effector functions to eliminate invading pathogens and modulate the adaptive as well as the innate immune response. Neutrophil function must be tightly regulated during inflammation and infection to avoid additional tissue damage. Increasing evidence suggests that transcription factors (TFs) function as key regulators to modulate transcriptional output, thereby controlling cell fate decision and the inf...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/jlb.1ru1219-504rr

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
ORCID:
0000-0001-6553-9291
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Oxford college:
Wolfson College
Role:
Author
ORCID:
0000-0002-6716-2528
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Publisher:
Wiley Publisher's website
Journal:
Journal of Leukocyte Biology Journal website
Volume:
107
Issue:
3
Pages:
419-430
Publication date:
2020-01-17
Acceptance date:
2019-12-18
DOI:
EISSN:
1938-3673
ISSN:
0741-5400
Pmid:
31951039
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1083975
Local pid:
pubs:1083975
Deposit date:
2020-05-22

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