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Thesis

Engineering human neural networks: controlling cell patterning and connectivity

Abstract:

Restorative treatments for diseases affecting the central nervous system (CNS) are difficult to develop, due to the complexity of CNS tissues and transferability issues with results from costly animal models. There is an urgent need to produce reliable, complex culture models to develop effective treatments. Such models require controlled interfaces and relevant dense neural cultures. In this thesis, techniques are developed to prepare and investigate scaffolds enabling complex structured ...

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Institution:
University of Oxford
Oxford college:
Wolfson College
Role:
Author

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Department:
Engineering Science
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
UUID:
uuid:4e001300-0971-43a1-a4eb-320aa8754498
Deposit date:
2019-07-04

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